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by Heby-Henricson, K. et al.Department of Biosciences and Nutrition, Karolinska Institutet, Huddinge, Sweden Consistent with previous reports, medulloblastomas and rhabdomyosarcomas developed in...

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by Mullany, L.K. et al.Department of Molecular and Cellular Biology, Baylor College of Medicine, One Baylor Plaza, Houston Texas 77030Wild-type tumor repressor protein 53 (Trp53) promotes ovarian...

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by Li, Q. et al.Arizona Cancer Center, University of Arizona, Tucson, Arizona 85724, USAHence, loss of Hsf1 activity not only suppressed p53 function, but also led to reduced sensitivity to killing by...

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by Yin, B. et al.Cell and Molecular Biology Graduate Group, University of Pennsylvania School of Medicine, Philadelphia, USAGermline Artemis(-/-) p53(-/-) mice die of lymphomas with antigen receptor...

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by Elyada, E. et al.The Lautenberg Center for Immunology, IMRIC, Hebrew University-Hadassah Medical School, Jerusalem 91120, IsraelThe transition from benign adenomas to invasive colorectal cancer in...

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by Slatter, T.L. et al.Department of Pathology, School of Medicine, University of Otago, Dunedin, New ZealandWe predict that by keeping B-cell populations in check, p53-dependent apoptosis prevents...

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by Barlow, J.L. et al.Medical Research Council Laboratory of Molecular Biology, Cambridge, UKA p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q- syndrome.Nat. Med....

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by Sluss, H.K. et al.Department of Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, USASimilar to DNA damage induced by ionizing radiation, expression of c-Myc in...

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by Tonks, I.D. et al.Queensland Institute of Medical Research, Herston, Queensland, AustraliaOn the basis of the collective data from Rb1 and Trp53 knockout mouse models, it seems that the conversion...

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by Hirota, Y. et al.The Perinatal Institute, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, USAWe further generated evidence to suggest that deletion of...

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by Geng, Y. et al.Department of Pathology, University of Alabama at Birmingham, USAConfocal microscopy analysis of STS-treated cells revealed partial colocalization of p53 with the mitochondrial...

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by Xu, Y. et al.Center for Comparative Oncology, University of California, Davis, CA 95616, USASNF5, a core component of the SWI/SNF complex, is necessary for p53 expression and cell survival, in part...

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by Yan, H. et al.Department of Veterinary & Animal Science, 661 North Pleasant St., Integrated Sciences Bldg., University of Massachusetts-Amherst, USATransplantation of Trp53+/- ductal...

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by Lim, S.O. et al.Department of Biological Sciences, Seoul National University, Seoul, Republic of KoreaWe found that p53 wild-type (WT) induced the degradation of Snail protein via murine double...

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by Jiang, Z. et al.Division of Cell and Molecular Biology, Toronto General Research Institute-University Health Network, Toronto, Ontario, CanadaThese results establish a causal role for Rb loss in...

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by Post, S.M. et al.Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USAp53-dependent senescence delays Emu-myc-induced B-cell lymphomagenesis.Oncogene....

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by Jabbour, A.M. et al.Children's Cancer Centre, Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, AustraliaWe conclude that p53 protein is activated after IL-3 deprivation...

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by Kelly, R.M. et al.Division of Hematology, Oncology, and Blood and Marrow Transplantation, University of Minnesota, USAShort-term inhibition of p53 combined with keratinocyte growth factor improves...

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by Zhao, Z. et al.Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724, USAWe show that p53 inactivation strongly cooperates with oncogenic Kras(G12D) to induce aggressive AML, while both...

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by Tomasevic, G. et al.Division of Experimental Brain Research, Wallenberg Neuroscience Center, Lund University Hospital, SwedenAlthough our results suggest that lack of the p53 gene results in...

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by Giglio, S. et al.Institute of Neurobiology and Molecular Medicine, CNR/Fondazione Santa Lucia, ItalyRegulation of MDM4 (MDMX) function by p76(MDM2): a new facet in the control of p53...

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by Stegh, A.H. et al.Belfer Institute for Applied Cancer Science, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, USAWe show that nuclear Bcl2L12 physically and functionally...

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by Junttila, M.R. et al.University of California San Francisco, Department of Pathology and Helen Diller Family Comprehensive Cancer Center, San Francisco, California 94143-0502, USASelective...

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by Nigam, N. et al.Proteomics Laboratory, Indian Institute of Toxicology Research (CSIR), M.G. Marg, P.O. Box 80, IndiaInduction of apoptosis by [6]-gingerol associated with the modulation of p53 and...

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by Guikema, J.E. et al.Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, MA 01655, USAWe show that p53 inhibits DNA breaks and mutations in S...

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by Elsaid, A.F. et al.Molecular Toxicology Interdepartmental Program, University of California at Los Angeles, Los Angeles, California, USASensitivity to cadmium-chloride-induced forelimb ectrodactyly...

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by Walter, M.A. et al.Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, UCLA, Los Angeles, California, USA(18)F-FDG small-animal PET can be used to visualize onset and...

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by Wang, W.L. et al.Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USALens fiber cell differentiation and denucleation are disrupted through expression of the N-terminal...

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by Theus, M.H. et al.The Miami Project to Cure Paralysis and Department of Neurological Surgery, University of Miami, Miami, Florida 33136, USAEphB3 limits the expansion of neural progenitor cells in...

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by Cheema, A. et al.Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, USAFurther, they imply that the pleiotropy of effects by which SUMO-1 influences...

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by Liu, D. et al.Division of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, USAThe knock-in mice exhibit constitutive p53 activation and segmental progeria that is...

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by Li, M. et al.Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX 77030, USAThe ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis.Proc. Natl. Acad....

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by Qin, Q. et al.Department of Basic Medical Sciences, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, USARole of calpain-mediated p53 truncation in...

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by Toko, H. et al.Department of Cardiovascular Science and Medicine, Chiba University Graduate School of Medicine, Chiba, JapanCaMKIIdelta plays a critical role in the development of heart failure in...

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by Jin, M.H. et al.Brain Korea 21 Project for Medical Science, Yonsei University College of Medicine, Seoul, KoreaToxic effects of lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on...

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by Ulanet, D.B. et al.Diabetes Center, University of California San Francisco, San Francisco, California, United States of AmericaDespite inhibition of p53 by Tag in this mouse PNET model, concomitant...

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by Wang, Y. et al.Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USACis lethal genetic interactions attenuate and alter p53 tumorigenesis.Proc. Natl. Acad. Sci....

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by Xiong, S. et al.Departments of Genetics and Veterinary Medicine and Surgery, The University of Texas M.D. Anderson Cancer Center Houston, TX 77030, USAMdm4 is thus a bona fide oncogene in vivo and...

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by Ikehata, H. et al.Department of Cell Biology, Tohoku University Graduate School of Medicine, Aoba-ku, Sendai, JapanInfluences of p53 deficiency on the apoptotic response, DNA damage removal and...

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by Kang, Y.H. et al.Institute of Bioscience, Department of Bioscience and Biotechnology, Sejong University, Seoul, Republic of KoreaAberrant V(D)J cleavages in T cell receptor beta enhancer- and...

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by Whibley, C. et al.Faculty of Medicine and Health, LIGHT Laboratories, University of Leeds, Leeds LS2 9JT, United KingdomWild-type and Hupki (human p53 knock-in) murine embryonic fibroblasts:...

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by Rubio, R. et al.Andalusian Stem Cell Bank, Centro de Investigación Biomédica, Consejería de Salud-Universidad de Granada, Granada, SpainMore importantly, p53(-/-) and p53(-/-)Rb(-/-) MSCs, but not...

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by Gendronneau, G. et al.Centre de Recherche en Cancérologie de l'Université Laval, Centre Hospitalier Universitaire de Québec, L'Hôtel-Dieu de Québec, QuébecThe complete loss of Hoxa5 function...

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by Cuesta, A. et al.Instituto de Investigaciones Biomédicas, Consejo Superior de Investigaciones Científicas, Madrid, SpainTransient transfection studies using plasmids that contain progressive...

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by Xia, Y. et al.Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USASiRNA-mediated reduction in the levels of beta-TrCP1 and other members of the...

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by Dhar, S.K. et al.Text changed: NPM enhances the expression of p53 target gene p21 and bax [Ref]. [See latest version]    [See changes]    [See complete history]

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by Hosako, H. et al.Department of Veterinary Physiology and Pharmacology, Texas A&M University, 434 VMR Building, College Station, USAGene and microRNA expression in p53-deficient day 8.5 mouse...

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by Efeyan, A. et al.Tumor Suppression Group, Spanish National Cancer Research Centre (CNIO), Madrid, SpainLimited role of murine ATM in oncogene-induced senescence and p53-dependent tumor...

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by Mancini, F. et al.Institute of Neurobiology and Molecular Medicine, National Council of Research, ItalyMDM4 (MDMX) localizes at the mitochondria and facilitates the p53-mediated intrinsic-apoptotic...

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by Yokoyama, M. et al.Inhibition of endothelial p53 improves metabolic abnormalities related to dietary obesity.Cell. Rep. 2014; 5:1691-703[See paper]

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